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[10] The study found that 62 percent of the patients who were using metformin had reduced plasma magnesium levels, while 45 percent of patients who were using PPIs also had reduced magnesium (these medications are often co-prescribed)
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The safety profiles as well as future directions including their potential application in improving COVID-19 patient outcomes have also been discussed in detail
That dissociation is the strongest practical argument for treating cerebrospinal fluid and plasma markers in these trials as exploratory readouts of target engagement rather than as stand-ins for benefit
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